# cytoo.com

> DEEP INSIDE THE MUSCLE, FOR A BETTER LIFE


## Posts

- [🔬 Turn Your Cell Images Into Powerful Therapeutic Insights with AI-Powered Phenotyping](https://cytoo.com/ai-powered-phenotypic-profiling-platform-cytoo/): Behind every microscopy image lies a wealth of information about cellular treatment response.
- [🔬 Monitoring lipid accumulation in muscle cells with imaging](https://cytoo.com/lipid-accumulation-in-muscle-cells-with-imaging/): An imaging-based approach to monitor fatty acid uptake and lipid accumulation in vitro provides spatially resolved, quantitative, and dynamic data at the single-cell level, enabling a deeper understanding of lipid metabolism, disease mechanisms, and drug effects.
- [🚀 Powering Precision: Functional Potency Assays by CYTOO](https://cytoo.com/powering-precision-functional-potency-assays/):  CYTOO develops functional potency assays to ensure batch consistency, biological activity, and regulatory compliance for gene therapies and biologics.
- [Revolutionizing Target Validation with Disease-Relevant Cellular Models](https://cytoo.com/target-identification-target-validation-dmd/): What's the risk of using cellular models that lack disease-specific pathways for target validation❓
- [Need spatially organized cell cultures for your advanced cell-based assays?](https://cytoo.com/cytoochips-advanced-cell-based-assays/): Discover CYTOOchips™ – high-precision micropatterned coverslips that control cell shape, position, and organization for more reproducible and physiologically relevant results.
- [🧬 Finally, muscle disease models that actually predict clinical success.](https://cytoo.com/disease-modeling-dm1/): CYTOO's MyoScreen™ transforms real patient cells into powerful screening tools that actually predict therapeutic success. 
- [💊 Small molecules, peptides, biologics...](https://cytoo.com/hit-identification-myoscreen/): 💊 Small molecules, peptides, biologics... Whatever your compound class, CYTOO's MyoScreen™ platform delivers reliable HIT IDENTIFICATION results for your next drug discovery campaign.
- [New milestone in Pompe Disease modeling!](https://cytoo.com/pompe-disease-modeling/): We’re excited to share our latest publication developing a muscle human model distinguishing late-onset from early-onset Pompe Disease in a HT/HC format.
- [MyoScreenTM, a High-Content Screening Platform Enabling Muscle Drug Discovery](https://cytoo.com/myoscreen-a-high-content-screening-platform/): MyoScreen™ is an improvement of current in vitro muscle models, enabling a more predictive screening strategy for preclinical selection of the most efficacious candidates earlier in the discovery pipeline process.
- [Looking for more physiologically relevant assays in your research or drug discovery projects?](https://cytoo.com/cytooplates-for-drug-discovery/): Discover 𝗖𝗬𝗧𝗢𝗢𝗽𝗹𝗮𝘁𝗲𝘀™, our standardized micropatterned plates optimized for High-Content Screening (HCS).
- [Pioneering Muscle Pathology Modeling for Drug Discovery](https://cytoo.com/muscle-pathology-modeling-for-drug-discovery/): CYTOO brings 10+ years of expertise in transforming muscle drug discovery. Our proprietary MyoScreen™ platform turns conventional in-vitro muscle assays into robust, standardized, high-content analysis tools.

## Pages

- [Blog](https://cytoo.com/blog/): CYTOO’s News Join us on LinkedIn Follow us on LinkedIn Discover our latest articles
- [Cookies](https://cytoo.com/cookies/)
- [Politique de confidentialité](https://cytoo.com/politique-de-confidentialite/): Politique de confidentialite ARTICLE 1 : AVANT-PROPOS Le RGPD et vous… La protection des données personnelles est l’une de nos préoccupations majeures. La politique de confidentialité s’inscrit dans un contexte juridique marqué par le Règlement Européen sur la Protection des Données (Règlement UE 2016/679 du 27 avril 2016), applicable depuis le 25 mai 2018 et la Loi Informatique et Libertés n°78-17 du 6 janvier 1978 modifiée relatif à l’informatique, aux fichiers et aux libertés. Ainsi, la présente politique de protection des données a pour but de vous présenter : Le responsable de traitement des données à caractère personnel La manière dont sont collectées et traitées […]
- [Legal](https://cytoo.com/legal/): LEGAL I. Information about the publisher of the site This site is the property of CYTOO société anonyme à conseil d’administration, registered under SIREN 504844168 located at 7 parvis Louis Néel -38040 Grenoble cedex 9 Registration number in the Trade and Companies Register: 504844168 Individual tax identification number: FR27504844168. The director of publication of the site is Marc Le Bozec. E-mail: info@cytoo.com Phone : +33 (0)4 38 88 47 05 II. Information about the host of the site The hosting of the site is provided by HOSTINGER INTERNATIONAL LTD., registered company number HE 335138, located at 61 Lordou Vironos Street, […]
- [Privacy policy](https://cytoo.com/privacy-policy/): Privacy POLICY Go to the French version here ARTICLE 1: PREFACE The GDPR and you… The protection of personal data is one of our major concerns. Our privacy policy falls within a legal context defined by the European Data Protection Regulation (EU Regulation 2016/679 of 27 April 2016), applicable since 25 May 2018 and the French Data Protection Act No 78-17 of 6 January 1978, as amended, relating to data processing, files and freedoms. The purpose of this data protection policy is therefore to present you with: The personal data controller How your data is collected and processed. Personal data […]
- [CYTOOplates](https://cytoo.com/our-products/cytooplates/): Our Products CYTOOplates High-throughput screening What is a CYTOOplate? CYTOOplates are designed for High-Content Screening (HCS) and are fully compatible with standard HCS imaging platforms and lab automation instruments. These standard plates contain micropatterns precisely positioned at the bottom of each well. They are available in: 96-well plates: Suitable for moderate-throughput experiments. 384-well plates: Ideal for large-scale screening applications (availability depends on the selected micropattern family). Our CYTOOplates collection Starter Explore five different micropatterns in two sizes on a single plate to determine the optimal pattern and size for your cell line. Ask for a quote Standard Same patterns available […]
- [CYTOOchips](https://cytoo.com/our-products/cytoochips/): Our Products CYTOOchips Precision for live-cell imaging What is a CYTOOchip? The CYTOOchip is a 19.5×19.5 mm coverslip with micropatterns transferred by photolithography onto high-quality, low-fluorescence borosilicate glass. Compatible with all inverted microscopes, CYTOOchips fit perfectly into standard 6-well plates. Grid coordinates printed on the underside of the CYTOOchip enables precise tracking of the same cell/micropattern over time. When combined with CYTOOchambers, they provide an ideal solution for high-resolution live-cell imaging. Our CYTOOchips collection Starter Explore four different micropatterns in three sizes on a single chip to determine the optimal pattern and size for your cell line. Ask for a quote Standard […]
- [Homepage](https://cytoo.com/): Deep inside the muscle, for a better life Genetic disorders Metabolic Disorders Neuromuscular disorders Pioneering muscle pathology research with CYTOO’s exclusive MyoScreen™ platform to accelerate drug target identification and therapeutic innovation Accelerate your discovery now Discover MyoScreen™ platform Trusted by industry leaders CYTOO supports your Research & development of drug candidates Discover our highly personalized approach through our different services Disease Modeling Developing patient-derived muscle disease models for drug discovery insights. Discover Target Identification & Validation Identifying therapeutic targets with functional models to de-risk drug discovery. Discover Hit Identification & Confirmation Supporting therapeutic discovery with reproducible muscle disease screening. Discover […]
- [Functional Potency Assays for Batch Release](https://cytoo.com/functional-potency-assays-for-batch-release/): Functional Potency Assays for Batch Release Our expertise in Functional Potency Assays for Batch Release CYTOO develops and implements functional potency assays to support batch release by demonstrating biological activity, ensuring consistency and achieving regulatory compliance, particularly for gene therapies and biologics. Our approach Using our MyoScreen™ platform, we establish robust, quantitative in vitro assays that go beyond biomarker detection to measure actual functional outcomes in skeletal muscle cells. For gene therapies, we have developed and patented methods to quantify both transgene expression and the functional activity of the encoded protein, addressing a key regulatory requirement for potency testing. Our assays […]
- [Lead Profiling & Mechanism of Action](https://cytoo.com/lead-profiling-mechanism-of-action/): Lead Profiling & Mechanism of Action Our expertise CYTOO characterizes and differentiates lead candidates by assessing their efficacy, specificity, and mechanism of action in physiologically relevant skeletal muscle models. This generates functional data that supports candidate selection and de-risking of development programs. Our approach We profile lead candidates across multiple donors and assays to evaluate the consistency and robustness of response. By combining high-content imaging, quantitative morphological and functional assays, and transcriptomic analyses, we investigate compound effects at both the cellular and molecular levels. Mechanistic studies include dose-response profiling, time-course experiments, and target/pathway modulation using pharmacological and genetic tools. This integrative approach […]
- [Hit Identification & Confirmation](https://cytoo.com/hit-identification-confirmation/): Hit Identification & Confirmation Our expertise in hit identification & confirmation CYTOO supports the identification and confirmation of small molecules, biologics, or gene therapies that modulate disease-relevant phenotypes in skeletal muscle. Our platform enables robust, reproducible hit discovery aligned with disease biology and clinical relevance. Our approach Using our MyoScreen™ platform, we perform phenotypic or target-based high-content screening, combining disease-relevant assays with automated image acquisition and AI-powered analysis. We screen diverse compound libraries on patient-derived models and confirm hits through orthogonal readouts and multi-donor validation.  Our assays are designed to detect subtle but meaningful phenotypic shifts that are often missed […]
- [Target Identification & Validation](https://cytoo.com/target-identification-validation/): Target Identification & Validation Our expertise By leveraging our physiologically relevant in vitro models and screening expertise, we reveal and validate novel therapeutic targets that the onset and progression of skeletal muscle diseases. We generate robust, functional data that supports target selection and de-risks early-stage drug discovery programs. Our approach We use our MyoScreen™-based disease models in combination with high-content imaging and high-throughput screening capabilities to perform siRNA and CRISPR library screens.  Our large panel of patient-derived and healthy donors allows us to assess target effects across different genetic backgrounds, while our quantitative phenotypic assays support mechanistic and functional validation. This […]
- [Disease modeling](https://cytoo.com/disease-modeling/): Disease Modeling Our expertise in disease modeling CYTOO develops physiologically relevant and robust in vitro models of skeletal muscle diseases using patient-derived cells. Our disease models recapitulate key pathological hallmarks and are designed to bridge discovery and translation towards the clinic. Our approach We combine our MyoScreen™ platform with deep biological insights, high-content cellular imaging and advanced data science. Our data-driven phenotypic analysis, powered by machine learning and statistical modeling, enables the detection of subtle and complex disease-related features that are beyond the reach of conventional methods. Automated image acquisition and processing workflows ensure scalability, reproducibility and throughput for drug discovery […]
- [About us](https://cytoo.com/about-us/): About CYTOO CYTOO is a Contract Research Organization (CRO) specializing in the modeling of human muscle pathologies with the capacity to support all stages of drug discovery. The company was cofounded in 2008 by Jacques Lewiner, a renowned physicist and inventor known for his significant contributions to the fields of physics, medical imaging, and telecommunications, and today combines scientific excellence with technological innovation. Our proprietary platform MyoScreen™, enables custom in vitro discovery services, from disease modelling and target identification to high-content compound screening and the development of GMP-compliant potency assays for batch release. By early 2026, CYTOO will operate cGMP-certified […]
- [Our products](https://cytoo.com/our-products/): Master cell organization with CYTOO’s micropatterns Optimized solutions for research and high-throughput screening. What is a micropattern? Micropatterning is the miniaturization of adhesive patterns using lithography techniques. Widely used in cell biology, this technology allows precise control over cell adhesion, migration, and 2D/3D confinement. By restoring key mechanical properties such as geometry, architecture, composition, mechanics, and dynamics, micropatterning brings in vitro conditions closer to physiological reality. CYTOO has developed extensive expertise in designing and producing optimized micropatterns for various cell types and research applications. Our advanced photolithography technology ensures exceptional precision and reproducibility. Our solutions: two formats to fit your […]
- [MyoScreen Platform](https://cytoo.com/myoscreen-platform/): MyoScreen™ Discovery Platform CYTOO provides unprecedented research capabilities that address the specific challenges our clients encounter over the entire drug development process. This is made possible by our unique expertise in micropatterning technology and extensive experience in creating in vitro models of human muscle pathologies as well as advanced analytical methods. The MyoScreen™ technology CYTOO’s MyoScreen™ technology is designed to facilitate advanced muscle cell research. By leveraging advanced micropatterning techniques, MyoScreen™ creates highly controlled and standardized environments for the culture and differentiation of myoblasts. This approach ensures uniformity and reproducibility, providing it ideal for high-throughput and high-content analysis, drug discovery, […]


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