🔬 Monitoring lipid accumulation in muscle cells with imaging

Monitoring lipid accumulation in muscle cells with imaging - CYTOO
An imaging-based approach to monitor fatty acid uptake and lipid accumulation in vitro provides spatially resolved, quantitative, and dynamic data at the single-cell level, enabling a deeper understanding of lipid metabolism, disease mechanisms, and drug effects.

Based on its MyoScreen™ platform, CYTOO developed: 

  • A myosteatosis model to identify new targets and drugs
  • A robust lipid accumulation screening assay for target identification and siRNA screening

 

Our lipid accumulation assay is particularly relevant for determining efficacy of small molecules to reduce lipid content and provides spatial, quantitative, and dynamic information that other biochemical methods can’t fully capture.

Key capabilities:

📍 Spatial resolution — seeing where lipids go

⏱️ Dynamic monitoring — tracking uptake over time

📊 Quantitative and single-cell information

🔍 Mechanistic insight into metabolic pathways

💊 Drug screening and disease modeling

🧪 Reduced sample destruction and multiplexing

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