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Cancer Cachexia: Protect the Muscle, Screen the Myotoxicity
Losing muscle with age is not a cosmetic issue. It is the loss of independence.
GLP-1 Muscle Loss: Which Agents Actually Preserve Muscle
Roughly one third of the weight lost on today’s leading incretin therapies is not fat.
Muscle Wasting Assay: Which Pathway a Drug Rescues
Very few tell you which pathways it worked on. Four pathways drive muscle loss. Most assays tell you a compound
Can an ALK5 inhibitor preserve muscle better than bimagrumab?
We put the question to the test at the Obesity & Weight Loss Drug Development Summit in Boston, and the
🎯HIT identification in muscle drug discovery: how many of your “hits” actually hold up?
Most screening teams already know the answer — and it’s not good.
Standard 2D assays generate volume, but oversimplified biology
Microscopic pretzels that could be a game-changer in drug discovery. 🥨🔬
No, this isn’t a random metaphor.
When acetylcholine receptors (AChR) organize on the surface of a myotube, they form pretzel-like