Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics

PLoS Genet. 2015 Mar 24;11(3):e1005063. doi: 10.1371/journal.pgen.1005063. eCollection 2015.

 

  • Raju D
  • Schonauer S
  • Hamzeh H
  • Flynn KC
  • Bradke F
  • Vom Dorp K
  • Dörmann P
  • Yildiz Y
  • Trötschel C
  • Poetsch A
  • Breiden B
  • Sandhoff K
  • Körschen HG
  • Wachten D.
Link: 
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005063

Keywords:

  • GBA2
  • GlcCer
  • cytoskeleton
  • sertoli
  • filopodia
  • lamellipodia
  • Signaling

Application: