Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells

 Cancer Res. 2011;71(1):134–142.

  • Woldemichael GM
  • Turbyville TJ
  • Linehan WM
  • McMahon JB
Link: 
http://www.ncbi.nlm.nih.gov/pubmed?term=Carminomycin%20I%20is%20an%20apoptosis%20inducer%20that%20targets%20the%20Golgi%20complex%20in%20clear%20cell%20renal%20carcinoma%20cells

Keywords:

  • high-throughput screening assays
  • clear cell renal cell carcinoma (CCRCC)
  • Von Hippel-Lindau (VHL) tumor suppressor gene
  • Golgi sequestration
  • P-gp-mediated localization of anticancer compounds
  • disk and L shaped fibronectin micropattern

Application: